new genetic test results

[mellowtigger]

A few weeks back, I bought a new 23AndMe test kit. I wanted testing on newer chip technology. The results are finally back.

On my "Carrier Status" report, I have no detections at all. That's good news.

On my "Health Predisposition" report, I have only two conditions detected.

1. Age-Related Macular Degeneration - "Increased risk", with 2 markers tested
   
   • I have the "C" variant for Y402H, gene CFH, marker rs1061170. I have 2 copies, which means both of my parents likely have their own copies too.
   • I have the "T" variant for A69S, gene ARMS2, marker rs10490924. I have only 1 copy, so only one of my parents would have that too.


2. Hereditary Hemochromatosis (HFE-Related) - "Variant detected, not likely at increased risk", with 2 markers tested
   
   • I have the "G" variant for H63D, gene HFE, marker rs1799945.  I have only 1 copy.  My mother was told recently by a doctor about her own risk for hemochromatosis, so I'm reasonably sure that I got my copy from her.  Wikipedia says this trait is particularly common in people of Celtic descent.
   • I was normal on the other variant tested, which means I have very low risk of developing iron accumulation problems myself.  My body can create the proper proteins to metabolize iron safely.

Still, after all these years, 23AndMe provides no risk predisposition assessment for the many genes already associated with autism.  I still want to update my assessment, but I have too many other things to ponder (and avoid) these days.  It's very unlikely to happen any time soon.