mellowtigger: (Terry 2021)

Please keep wearing your N95 mask out there in the world, when you're around other people.

Because SARS-CoV-2 infection causes blood clots which can damage any organ in the body, and because SARS-CoV-2 can directly infect so many tissues, it therefore produces a wide variety of illness. It causes all sorts of problems that were possible even before this virus showed up, so it's hard to isolate the signal of what this specific virus is doing to humanity when contrasted against other potential factors. It infects the organs that have immune privilege: the brain, eyes, and testicles. Even though there is some evidence that people are newly catching COVID less frequently than before, the lower incidence doesn't matter if these infections are permanent because of the immune privilege and other methods of persistence, staying in multiple reservoirs.

Long COVID is real and increasing. It's real in adults, it's real in children, and it maybe affects as many as 6 million children in the USA. SARS-CoV-2 is known to cause a long list of damages like: heart damage, anemia, liver injury, spleen enlargement, kidney and intestine damage, POTS, brain fog, and other autonomic dysfunctions, plus the well known pneumonia, plus the well-known heart attacks and strokes, plus the immune system damage.

It makes me sad to learn the stories of real people whose families are affected by problems that I know to be associated with SARS-CoV-2 infection. No matter how many times you've had COVID before, it's worthwhile to not get COVID again. I still wear my mask around other people. Please, be safe out there.

And, if you're noticing symptoms, maybe try one of the locations in this list to see if someone can help you test for specific issues and find reasonable actions to take in response.

busy

2026-Mar-03, Tuesday 04:45 pm
mellowtigger: (Default)

During the last few days, I've managed to check various bills and paid them off. That's good. I checked the bank afterwards, and I'm still surprised at how much money I've stored away. It's minuscule compared to what anybody would recommend, but I'm doing so much better than most Americans in the USA. I seriously need to work on finding someone who can build new steps for me at the front and back doors to the house. The back is literally rotting out, so I have to watch my step when I take the trash to the dumpster.

As for work, it seems busier than expected at my job this spring semester, and I don't understand why. I had a 15-minute trash video I wanted to watch today on YouTube, and I got about 8 minutes into it throughout the whole day. No spare time for trivialities between tickets.

Again speaking of work, I'm not really a fan of the "New" experience in Microsoft applications like Outlook. I needed to clear Outlook cache for someone today, and it's not obvious how to do it in the new environment. I tried these 4 simple steps from Microsoft, and they actually worked to solve the problem the user was having! And it doesn't require local administrator privileges either, which is great.

A bit of good news: Physics Girl has posted a new YouTube video! It's an 8-minute video about solar physics and neutrinos. At the end, she talks very briefly about her Long Covid experience. It's good, though, that she's well enough to do a video again, even if it's filmed while she's still in bed.

remember SARS-CoV-2?

2025-Jun-23, Monday 09:09 pm
mellowtigger: (biohazard)

I haven't written much about SARS-CoV-2 this year. It's still out there, despite the television news not really mentioning much of anything any more. Today, I wanted to share some tidbits that are interesting or worrying, while simultaneously avoiding my Doom Bingo 2025 topics. I'm also avoiding a lot of old 2022 studies that showed persistent infection in the brain and various kinds of physical damage in the brain after infection. I tried to keep these links a lot more "fresh" and recent.

Click to see a little of the bad news in no particular order...

The good news? There is some.

Click to read the proverbial silver lining...

  • This pre-print makes some interesting claims. Researchers found damage to the brainstem and cerebellum that might explain a variety of Long Covid symptoms. Notably, "While viral genetic material was detectable, infected neurons were not observed." This observation gives hope that we can become infected and sometimes not develop persistence within the brain. It might be imported from other areas of the body instead, maybe tissue without immune privilege, so the ongoing infection could eventually be cured. Within the downloaded PDF of the full article, they suggest that the virus damages the immune system, resulting in auto-immune problems that affect these outcomes in the brain, although these details are well above my level of understanding.
    "Brainstem Reduction and Deformation in the 4th Ventricle Cerebellar Peduncles in Long COVID Patients: Insights into Neuroinflammatory Sequelae and “Broken Bridge Syndrome”

  • This study offers another kind of hope. "Here we demonstrate extensive endothelial cell (EC) death in the microvasculature of COVID-19 organs. Notably, EC death was not associated with fibrin formation or platelet deposition, but was linked to microvascular red blood cell (RBC) haemolysis." As I interpret it, red blood cells are "jumping on a live grenade" to save you from circulatory system damage, and these kinds of clots might respond to new drugs that current blood thinning drugs don't help. That's good news too, despite the macabre horror of it.
    "Ischaemic endothelial necroptosis induces haemolysis and COVID-19 angiopathy"

  • This study notes that "SARS-CoV-2 infection is known to cause changes in the T cell compartment, including differences in expression of receptors associated with exhaustion. While immune responses to infection and vaccination are not equivalent, in the eyes of the public, this concern of immune exhaustion after infection can carry over to vaccination." They found that repeat vaccination does not lead to T-cell exhaustion. That finding is good news. I've mentioned before that spike protein (whether virus or vaccine) carries its own dangers, but at least immune system reduction doesn't seem to result from vaccination, just infection.
    "No evidence of immune exhaustion after repeated SARS-CoV-2 vaccination in vulnerable and healthy populations"

Sorry, that's a lot of information, even after I deleted half a dozen articles that I included on the first draft. :(

I still mask around other people. No matter how many times you've had COVID, it's better not to get it even one more time. Stay safe out there.

mellowtigger: http://wikiality.wikia.com/Breaking_News#Shocking_News:_Stephen_Colbert_Predicts_The_Future.21 (i told you so)

Long time readers here will learn nothing new in this very important article, but it is validation of what I have been warning about for years. Thanks to [personal profile] andrewducker for finding this gem. A doctor from the Icahn School of Medicine at Mount Sinai does a radio interview with CBC (Canadian Broadcasting Corporation). The doctor doesn't mention blood clots or T-cell infection but does forcefully confirm the following details:

  • persistent infection
  • persistent infection because immune privileged tissue like the brain gets infected
  • immune system damage
  • T-cell exhaustion
  • failure to suppress other diseases because of immune damage
    (which is essentially my Doom Bingo 2025 topic of C-AIDS but without using that terminology yet)

"There is no such thing as a COVID infection without consequence"
- https://www.cbc.ca/radio/quirks/beyond-long-covid-1.7485888,
"Beyond long COVID — how reinfections could be causing silent long-term organ damage"

I recommend hitting the play button near the top of that article and listening to the 20-minute interview. The text summary is good and covers the major topics, but it is incomplete. I like that particular quote the most. Stay safe out there. Keep masking, at least until all indoor spaces are well sanitized with filtration. I still need to send this info to my city, county, state, and national representatives.

mellowtigger: (roulette)

An important overview paper about SARS-CoV-2 was published from The Medical Journal Of Australia online yesterday. It cites a lot of other papers, summarizing what's known about some of the issues I've been warning about here for a while. It focuses on things like immune dysregulation and viral persistence. This article has a long title with a bit of hope in it: "Towards a cure for long COVID: the strengthening case for persistently replicating SARS-CoV-2 as a driver of post-acute sequelae of COVID-19". Note, however, that it doesn't mention virus in neurons as another (non-curable) method of persistence. It only mentions the 2 methods of persistence (gut, and bone marrow/immune system) as potentially curable paths of persistence.

As always, I encourage everyone to keep masking. I do it myself every time I'm around other people.

I've decided to do something different in 2025. I know that even when restricting my doom-and-gloom posts to Moody Monday, that's still a lot of negativity that nobody needs in trying times. So I'm going to try transforming it into something almost "fun" for next year.

Near the end of 2024, I intend to post my Doom Bingo 2025 card. I will have each square with a topic that I expect to appear in 2025 as "Something Bad That Happens". I might even include some links for why I predict it will appear in the course of the year. During the year, however, I will not post about that topic. Really! Instead, as evidence piles up, I'll keep a folder of news clippings that I can use in December 2025 to determine if I "win" the bingo card for that year.

Now, I may post tangent topics, like helpful things to do to prepare for the troubles. I won't, however, post warnings any more. The time for warnings is over. Either my sense of trends is right or wrong. A Bingo game might make even bad news seem less traumatic. If nothing else, it'll keep this blog a little more like it used to be in the old days, focused more on interesting things to learn or do, or the fun intersection between many topics.

So, stay tuned. My planned Doom Bingo 2025 card will show up here soon. :) Finally, some relief from the stressful topics.

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